By John G. Bartlett MD
Designed to supply easy access to criteria of deal with infectious affliction by way of targeting choice, right doses, charges, and negative effects of antimicrobial brokers, the 2005-2006 notebook of Infectious affliction Therapy attracts largely from thoughts made by means of the facilities for affliction keep an eye on and Prevention, the clinical Letter on medicinal drugs and Therapeutics, and from legit statements of revered scientific societies. Tabular fabric has been up to date to incorporate all newly authorized antibiotics, in addition to new concepts for management.
This version contains topical matters resembling MRSA (USA three hundred strain), Avian influenza, Acinetobacter Hepatitis B virus (HBV), hepatitis C virus (HCV), and bioterrorism. It additionally includes the hot directions for pyogenic meningitis, diabetic foot infections, healthcare linked pneumonia, surgical prophylaxis, fungal infections, bacteruria, and administration of infections linked to foreign travel.
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Extra resources for 2005-2006 Pocket Book of Infectious Disease Therapy
Telithromycin is also active agent against multi-drug resistant Streptococcus pneumoniae. 41 ANTIMICROBIAL DOSING REGIMENS IN RENAL FAILURE A. GENERAL PRINCIPLES 1. Initial dose is not modified in renal failure. 2. Adjustments in subsequent doses for renally excreted drugs may be accomplished by a) giving the usual maintenance dose at extended intervals, usually three half-lives (extended interval method); b) giving reduced doses at the usual intervals (dose reduction method); or c) a combination of each.
Trachomatis—ofloxacin; S. pneumoniae—levofloxacin; gatifloxacin, or moxifloxacin, or gemifloxacin; anaerobes—gatifloxacin and moxifloxacin are most active; ciprofloxacin and levofloxacin are least active. 7. Beta-lactam-beta-lactamase inhibitor. Amoxicillin + clavulanate (Augmentin), ticarcillin + clavulanate (Timentin), ampicillin + sulbactam (Unasyn), and piperacillin + tazobactam (Zosyn). 8. Macrolides: Erythromycin, clarithromycin, azithromycin, dirithromycin. * Oral cephalosporins; cefuroxime has both oral and parenteral formulations.
Oral cephalosporins; cefuroxime has both oral and parenteral formulations. † Telithromycin is also active agent against multi-drug resistant Streptococcus pneumoniae. 41 ANTIMICROBIAL DOSING REGIMENS IN RENAL FAILURE A. GENERAL PRINCIPLES 1. Initial dose is not modified in renal failure. 2. Adjustments in subsequent doses for renally excreted drugs may be accomplished by a) giving the usual maintenance dose at extended intervals, usually three half-lives (extended interval method); b) giving reduced doses at the usual intervals (dose reduction method); or c) a combination of each.
2005-2006 Pocket Book of Infectious Disease Therapy by John G. Bartlett MD